A research program in interpretable biomedical AI.

Selected manuscripts and a complete scholarly record spanning biomedical representation learning, computational genomics, medical imaging, explainable AI, and biological data science.

Current Manuscripts & Preprints

5 current works
  1. 01
    Mostafa S, Jiang Y, Zou J, Massoud TF, Alizadeh AA, Diehn M, Xing L, Islam MT
    Nature Communications· Under review · 2026
  2. 02
    Mostafa S, Zou J, Alizadeh AA, Diehn M, Xing L, Islam MT
    Nature Computational Science· Under review · 2026
  3. 03
    Mostafa S, Diehn M, Alizadeh AA, Xing L, Islam MT
    Nature Biomedical Engineering· Under review · 2026
  4. 04
    Xue Y*, Mostafa S*, Zou J, Liao J, Diehn M, Alizadeh AA, Xing L, Islam MT
    Nature Biomedical Engineering· Preparing for submission · 2026* Equal contribution
  5. 05
    Yesiloglu R, Mostafa S, Zou J, Alizadeh A, Wu J, Xing L, Adeli E, Islam MT
    Nature· Preparing for submission · 2026

Recent Preprints & Conference Abstracts

3 selected works
  1. 01
  2. 02
    Mostafa S, Xue Y, Islam MT
    Biologically Informed Graph Neural Network Construction via Pathway-Based Gene-Interaction Graphs.
    Joint AAPM | COMP Annual Meeting· 2026Conference abstract
  3. 03
    Rahman A, Mostafa S, Xing L, Islam MT
    TechRxiv· 2025Single-cell integration

Cancer and Biomedical AI

1 paper
  1. 01
    Rahman A, Rahman A, Mostafa S, Islam MT
    Cross-Cancer Computational Framework for Immune-Dysregulated Ecosystem Discovery and Therapeutic Prioritization.
    Proc. IEEE CBMS · 2026

Neurological Disorder Diagnosis & Medical Imaging

6 papers
  1. 01
    Yin W, Mostafa S, Wu F-X
    Diagnosis of Autism Spectrum Disorder Based on Functional Brain Networks with Deep Learning.
    Journal of Computational Biology 28(2) · 2021 162 citations
  2. 02
    Mostafa S, Tang L, Wu F-X
    Diagnosis of Autism Spectrum Disorder Based on Eigenvalues of Brain Networks.
    IEEE Access 7 · 2019 98 citations IF 4.64 · Q1
  3. 03
    Tang L, Mostafa S, Wu F-X
    A Network Clustering-Based Feature Selection Strategy for Classifying Autism Spectrum Disorder.
    BMC Medical Genomics 12:153 · 2019 13 citations
  4. 04
    Jahan F, Shifat SM, Anannya FZ, Mostafa S, Hasan MM
    Dementia Patient Health, Prescriptions ML Dataset: LightGBM Classification of XAI-based LIME and SHAP for Dementia Detection.
    Proc. NSysS · 2024
  5. 05
    Mostafa S, Yin W, Wu F-X
    Autoencoder-Based Methods for Diagnosis of Autism Spectrum Disorder.
    ICCABS, LNCS 12029 · 2019 26 citations
  6. 06
    Guo H, Yin W, Mostafa S, Wu F-X
    Diagnosis of ASD from rs-fMRI Images Based on Brain Dynamic Networks.
    ISBRA, LNCS 12304 · 2020

Plant Phenomics & Agricultural AI

3 papers
  1. 01
    Mostafa S, Mondal D, Panjvani K, Kochian L, Stavness I
    Explainable Deep Learning in Plant Phenotyping.
    Frontiers in AI: AI in Food, Agriculture, Water 6 · 2023 80 citations
  2. 02
    Mostafa S, Mondal D, Beck M, Bidinosti C, Henry C, Stavness I
    Leveraging Guided Backpropagation to Select Convolutional Neural Networks for Plant Classification.
    Frontiers in AI 5 · 2022 23 citations IF 3.77 · Q2
  3. 03
    Mostafa S, Mondal D, Beck M, Bidinosti C, Henry C, Stavness I
    Visualizing Feature Maps for Model Selection in Convolutional Neural Networks.
    ICCV Workshops · 2021 Acceptance 25%

Software Engineering & Methodological CS

6 papers
  1. 01
    Mostafa S, Cynthia ST, Roy B, Mondal D
    Feature Transformation for Improved Software Bug Detection Models.
    Journal of Systems and Software 219 · 2025 IF 3.7 · Q1
  2. 02
    Mostafa S, Fahim MANI, Hossain ABMA
    A New Chaos-Based Medical Image Encryption Scheme.
    ICIEV · 2017 7 citations
  3. 03
    Fahim MANI, Mostafa S, Tasnim J, Hossain ABMA
    Alignment of 3-D Scanning Data for Polygonal Mesh based on Modified Triangulation.
    ICIEV · 2017
  4. 04
    Mostafa S, Fahim MANI, Tasnim J
    An Approach to Effective 3D Reconstruction Based on Point Cloud Merging.
    IEEE WIECON-ECE · 2016
  5. 05
    Jahiruzzaman M, Fahim MANI, Mostafa S, Hossain ABMA
    An Adaptive Reconfigurable Radix-2n FFT/IFFT Architecture.
    IEEE ICIEV · 2016
  6. 06
    Zahan N, Hossain ABMA, Mostafa S
    Simulation Study on Nonlinear Ultrasound Imaging Using Different Realistic Synthetic Phantoms.
    IEEE WIECON-ECE · 2015

Book Chapter

1 paper
  1. 01
    Mostafa S, Wu F-X
    Diagnosis of Autism Spectrum Disorder with Convolutional Autoencoder and Structural MRI Images.
    Neural Engineering Techniques for ASD, Academic Press · 2021 59 citations